Tell Qarqur is one of the largest archaeological sites in the Orontes River Valley of western Syria, rising some 30 meters above the surrounding plain. The site is located in the Hama administrative district, just south of the modern town of Jisr Shugur. Today, the region surrounding Tell Qarqur, known as the Ghab Basin, is agriculturally rich and possesses a hospitable Mediterranean climate.
Tell Qarqur has a large upper mound to the south and a smaller mound to the north, together covering approximately 10 hectares (25 acres). While these two mounds form the most conspicuous areas of ancient settlement, remains of occupation from various phases can be found extending at least 200 meters into surrounding fields.